7-Chlorokynurenic acid sodium salt
Supplier | MedChemExpress |
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Product # | HY-100811A-50 mg |
CAS # | 1263094-00-3 |
Pricing | 50 mg, USD $290.0 |
Synonyms | 7-CKA sodium salt |
MWt | 245.59 |
Formula | C₁₀H₅ClNNaO₃ |
Biological Activity | 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2]. |
Purity | 99.79% |