| Supplier |
CD Formulation |
| Product # |
PE-0416 |
| Pricing |
, Inquire for price
|
| product1 |
Pharmaceutical Excipients
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| Molecular Formula |
C7H12O4
|
| Molecular Weight |
160.17
|
| Applications |
It is used to prepare fruit and wine-flavored essences such as pears, apples, grapes, and cherries. It is used as flavoring agent, flavoring agent and solvent in pharmacy. This product is also an intermediate of organic synthesis. It is widely used in the production of dyes, spices, sulfonylurea herbicides, etc. It is mainly used to produce ethoxymethylene, barbituric acid, diethyl alkyl malonate, and then synthesize medicines such as norfloxacin, romefloxacin, Chloroquine, phenylbutazone, etc. and synthetic dyes and pigments such as benzimidazolone organic pigments. Diethyl malonate abroad is mainly used to produce ethoxymethylene, barbituric acid and diethyl malonate alkylate.
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| Safety |
This product is non-toxic and generally considered safe (FEMA). Rabbit skin application 500mg, moderate irritation; rat oral administration, LD50 is 14, 900 ul/kg, mouse oral administration, LD50 is 6400mg/kg, rabbit skin application, LD50>16ml/kg.
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| Incompatibilities |
This product may undergo oxidation, hydrolysis and other reactions when encountering strong oxidants, acids, alkalis and other substances.
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| Synonyms |
Propanedioic acid, diethyl ester; Malonic acid, diethyl ester
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| CAS Number |
105-53-3
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| Category |
Flavoring agent
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| Chemical Name |
1, 3-diethyl propanedioate
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| Grade |
Pharmceutical Excipients
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| Administration route |
Cutaneous, oral
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| Stability and Storage Conditions |
It is relatively stable under normal pressure and temperature. It will be degraded by acid, alkali, oxidizing and reducing agents. Should be placed in airtight containers, stored in a dry, cool place.
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| Source and Preparation |
This product is made by artificial synthesis. It is obtained by distillation and esterification of malonic acid and ethanol in azeotropic benzene medium. Or from sodium malonate and ethanol under the catalysis of sulfuric acid, after esterification and distillation.
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