Afuco™ Anti-Human Lewis Y ADCC Therapeutic Antibody (MB 311), ADCC Enhanced
Anti-Lewis Y ADCC Enhanced Antibody (MB 311) is an ADCC enhanced antibody produced by our Afuco™ platform. MB311 is a fully humanized monoclonal antibody recognizing the tumor-associated antigen Lewis Y. This carbohydrate antigen is expressed on 60-90 % of all epithelial cancers, with only limited expression on normal tissues, and thus represents an attractive target for cancer immunotherapy. MB311 was well tolerated, permeated into malignant effusion and attracted immune cells leading to decreased tumor cell counts in the effusion.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-468CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | Lewis Y |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | 4°C or -20°C, avoid repeated freezing and thawing. |