Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 1 (PIN1) Antibody
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx034932-80UL |
| Pricing | 80 µl USD $326.25 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB, IHC |
| UniProt Primary AC | Q13526 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |