BI 2536
BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.
Supplier | Selleck Chemicals |
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Product # | S1109 |
Sku # | S1109-50mg |
Pricing | 50mg, $670.00 |
Citations for this product:
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bioRxiv - Cell Biology 2020Quote: ... Drugs used in this work were 10 μM BI-2536 (S1109, Selleck Chemicals), 10 μM RO-3306 (Sigma-Aldrich ...
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bioRxiv - Cell Biology 2024Quote: For Plk1 inhibition: BI2536 (#S1109; Selleck Chemicals) was used at 100 nM
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bioRxiv - Cell Biology 2022Quote: ... Plk1: 10 nM BI2536 (Selleck Chemicals: S1109), ATR ...