Tyrosine-Protein Kinase ZAP-70 (ZAP70) Antibody
ZAP70 Antibody is a Rabbit Polyclonal antibody against ZAP70. This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx001807-50UL |
| Pricing | 50 µl USD $319.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB, IF/ICC |
| UniProt Primary AC | P43403 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |