DNA Methyltransferase 3 Like (DNMT3L) Antibody

DNMT3L Antibody is a Rabbit Polyclonal antibody against DNMT3L. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Supplier Abbexa Ltd.
Product # abx001899-200UL
Pricing 200 µl USD $696.0
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IHC
UniProt Primary AC Q9UJW3
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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