Tianeptine sodium
Tianeptine is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD445 |
| CAS # | 30123-17-2 (sodium) |
| Pricing | Customizable size, Inquiry |
| Synonym | Tianeptine; brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C21H24ClN2NaO4S |
| Exact Mass | 436.1224 |
| Molecular Weight | 458.9328 |
| Elemental Analysis | C, 54.96; H, 5.27; Cl, 7.72; N, 6.10; Na, 5.01; O, 13.94; S, 6.99 |
| IUPAC/Chemical Name | sodium 7-((3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino)heptanoate |
| InChi Key | ZLBSUOGMZDXYKE-UHFFFAOYSA-M |
| InChi Code | InChI=1S/C21H25ClN2O4S.Na/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);/q;+1/p-1 |
| SMILES Code | O=C([O-])CCCCCCNC(C1=CC=C(Cl)C=C12)C3=CC=CC=C3N(C)S2(=O)=O.[Na+] |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |