nAChR agonist 1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133011-10 mM * 1 mL |
| CAS # | 1394371-75-5 |
| Pricing | 10 mM * 1 mL, USD $495.0 |
| Biological Activity | nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease[1]. |
| Purity | 98.02% |
| MWt | 419.94 |
| Formula | C₂₀H₁₈ClNO₃S₂ |