Ulixertinib hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15816A-5 mg |
| CAS # | 1956366-10-1 |
| Pricing | 5 mg, USD $70.0 |
| Synonyms | BVD-523 hydrochloride; VRT752271 hydrochloride |
| MWt | 469.79 |
| Formula | C₂₁H₂₃Cl₃N₄O₂ |
| Biological Activity | Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2]. |
| Purity | 99.95% |