Microcrystalline Cellulose PH112
Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is commercially available in different particle sizes and moisture grades that have different properties and applications.
| Supplier | CD Formulation |
|---|---|
| Product # | PE0372 |
| Pricing | , Inquire for price |
| product1 | Suspending Agents |
| Molecular Formula | (C6H10O5)n n n≈220 |
| Molecular Weight | ≈36000 |
| Applications | Adsorbent; suspending agent; diluent for tablets and capsules; disintegrant for tablets. Microcrystalline cellulose PH112.is suitable for wet granulation. |
| Safety | This product is widely used in oral pharmaceutical preparations and food, and is a relatively non-toxic and non-irritating substance. This product is not absorbed after oral administration and has almost no potential toxicity. A large amount of use may cause mild diarrhea, and it is not difficult to use as a pharmaceutical excipient. Abuse of certain tablets containing cellulose, such as inhalation or injection administration, can lead to fibrous granulomas. |
| Incompatibilities | This product is incompatible with strong oxidizing agents. |
| Synonyms | Avicel PH 112; Celex PH112; cellulose-gel PH112; Celphere PH112; Ceolus-KG PH112; crystalline-cellulose PH112; E460 PH112; Emcocel PH112; Ethispheres PH112; Fibrocel PH112; Pharmacel PH112; Tabulose PH112; Vivapur PH112 |
| CAS Number | 9004-34-6 |
| Category | Adsorbent; Suspending Agents; Diluent for tablets and capsules; Disintegrant for tablets |
| UNII | OP1R32D61U |
| Chemical Name | Cellulose PH112 |
| Grade | Pharmceutical Excipients |
| Administration route | Oral; Topical |
| Dosage Form | Inhalation; Oral Capsule; Granules; Suspension; Syrup; Tablet; Topical and Vaginal |
| Stability and Storage Conditions | This product is a hygroscopic, but stable substance. Large quantities of storage must be placed in airtight containers in a cool and dry environment. |
| Source and Preparation | Microcrystalline cellulose can be obtained by controlled hydrolysis of α-cellulose with dilute mineral acid solution, and α-cellulose can be obtained from fiber pulp of cellulose-containing plants. After hydrolysis, the hydrolyzed cellulose is filtered and purified, and the water slurry is spray-dried to form dry porous particles with a wide particle size distribution. |