PROTAC SGK3 degrader-1

Supplier MedChemExpress
Product # HY-125878-5 mg
CAS # 2381320-35-8
Pricing 5 mg, USD $1250.0
Synonyms SGK3-PROTAC1
MWt 1157.38
Formula C₅₇H₇₃FN₁₀O₁₁S₂
Biological Activity PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate)[1].
Purity 99.32%
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