SB 203580 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10256A-50 mg |
| CAS # | 869185-85-3 |
| Pricing | 50 mg, USD $96.0 |
| Synonyms | RWJ 64809 hydrochloride |
| MWt | 413.9 |
| Formula | C₂₁H₁₇ClFN₃OS |
| Biological Activity | SB 203580 hydrochloride (RWJ 64809 hydrochloride) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. SB 203580 hydrochloride inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. SB 203580 hydrochloride is an autophagy and mitophagy activator[1]. |
| Purity | 99.71% |