VU6001966
VU6001966 is a potent and selective mGlu2 inhibitor and Negative allosteric modulator. VU6001966 has a mGlu2 IC50 = 78 nM and mGlu3 IC50 > 30 μM. It exhibits excellent central nervous system (CNS) penetration and represents an exciting lead series for potential mGlu2 PET tracer development.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1256 |
| CAS # | 2009052-76-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | VU6001966; VU-6001966; VU 6001966 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C17H15FN4O2 |
| Exact Mass | 326.1179 |
| Molecular Weight | 326.33 |
| Elemental Analysis | C, 62.57; H, 4.63; F, 5.82; N, 17.17; O, 9.81 |
| IUPAC/Chemical Name | 4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide |
| InChi Key | SSSNPJKQBYVHBV-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C17H15FN4O2/c1-22-7-6-13(21-22)10-24-16-9-20-15(17(19)23)8-14(16)11-2-4-12(18)5-3-11/h2-9H,10H2,1H3,(H2,19,23) |
| SMILES Code | CN1C=CC(COC2=C(C3=CC=C(F)C=C3)C=C(C(N)=O)N=C2)=N1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |