Anti-PNMT Antibody
PNMT, also known as Phosphatidylethanolamine N-methyltransferase, or PEMT, PEAMT, or PEMT2, and encoded by the gene PEMT/PEMPT/PNMT, catalyzes three sequential methylation reactions of phosphatidylethanolamine to produce phosphatidylcholine a major constituent of cell membranes and a primary pulmonary surfactant. PNMT/PEMT is localized to the endoplasmic reticulum membrane as well as the mitochondrial membranes. PNMT/PEMT is widely expressed and has the highest activity in the mitochondria. The conversion of phosphatidylethanolamine to phosphatidylcholine by sequential methylation via PNMT/PEMT occurs in the liver. A different pathway for phosphatidylcholine production starting from choline also is present in cells but it does not involve the PNMT/PEMT enzyme.
| Supplier | Creative Biogene |
|---|---|
| Product # | PAB1034 |
| Pricing | Inquiry |
| Research Area | Primary Antibodies/Antibody |
| Antibody Target | PNMT |
| Antibody Type | Polyclonal |
| Application | IHC, WB |
| Formulation | Buffer: 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Appearance | Liquid |
| Host | Rabbit |
| Species Reactivity | Human |
| Usage Statement | Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |