Anti-UQCRFS1 Antibody
The protein named Cytochrome b-c1 complex subunit Rieske, mitochondrial or alternatively Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, (RISP) or Ubiquinol-Cytochrome C reductase iron-sulfur subunit, and encoded by the human gene named UCRFS1, is part of a huge multi-protein complex called Complex III or Cytochrome B-C1 complex which is the respiratory chain that generates the electrochemical potential needed to produce ATP for cellular metabolism. The UCRFS1 protein gets cleaved into the active transit peptide called Cytochrome b-c1 complex subunit 11 or Complex III subunit IX or Ubiquinol-cytochrome C reductase 8 kDa protein. Complex III contains 11 subunits and 3 respiratory subunits. It is located in the mitochondrion inner membrane and it contains iron and sulfur so it is part of the iron-sulfur protein complex within the mitochondria. UQCRFS1 is a key subunit of the bc1 complex (Complex III) and it is often amplified in many cancers at the gene level in more aggressive forms, likely due to the need for increased ATP production.
| Supplier | Creative Biogene |
|---|---|
| Product # | PAB1052 |
| Pricing | Inquiry |
| Research Area | Primary Antibodies/Antibody |
| Antibody Target | UQCRFS1 |
| Antibody Type | Polyclonal |
| Application | WB |
| Formulation | Buffer: PBS with up to 0.1% sodium azide and 50% glycerol. |
| Appearance | Liquid |
| Host | Rabbit |
| Species Reactivity | Mouse |
| Usage Statement | Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |