DNA Polymerase Kappa (POLK) Antibody
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).
Supplier | Abbexa Ltd. |
---|---|
Product # | abx031322-80UL |
Pricing | 80 µl USD $326.25 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB |
UniProt Primary AC | Q9UBT6 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |