Doravirine-[13C6]
Labelled Doravirine. Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going.
| Supplier | BOC Sciences |
|---|---|
| Product # | BLP-001304 |
| Pricing | Inquire |
| Molecular Weight | 431.71 |
| Molecular Formula | C11[13C]6H11ClF3N5O3 |