B-Cell Lymphoma/leukemia 10 (BCL10) Antibody
Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN.Entrez Protein NP_003912.It is a protein containing a caspase recruitment domain (CARD).It plays an important role in apoptosis and activating NF-kappaB.The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling.Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma.MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx015774-100UL |
| Pricing | 100 µl USD $420.5 |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Host | Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |