Recombinant Monkey TNFRSF4 Protein, Fc-tagged, Alexa Fluor 647 conjugated

OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.
Supplier Creative Biomart
Product # TNFRSF4-549RAF647
Pricing 20ug : USD $798, 50ug : USD $1298, 100ug : USD $1998
Product Category Recombinant Protein
Shipping Country USA
Feedback