SNIPER(BRD)-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-111875-1 mg |
| CAS # | 2095244-54-3 |
| Pricing | 1 mg, USD $800.0 |
| Biological Activity | SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation of BRD4 via the ubiquitin-proteasome pathway. SNIPER(BRD)-1 also degrades cIAP1 , cIAP2 and XIAP with IC50s of 6.8 nM, 17 nM, and 49nM, respectively[1]. |
| Purity | 98.40% |
| MWt | 1056.73 |
| Formula | C₅₃H₆₆ClN₉O₈S₂ |