Pomalidomide-PEG1-C2-N3
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125843-100 mg |
| CAS # | 2271036-44-1 |
| Pricing | 100 mg, USD $980.0 |
| Synonyms | Cereblon Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 50 |
| MWt | 386.36 |
| Formula | C₁₇H₁₈N₆O₅ |
| Biological Activity | Pomalidomide-PEG1-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology. Pomalidomide-PEG1-C2-N3 can be used to design a selective CDK6 PROTAC degrader CP-10. CP-10 induces the degradation of CDK6 with an DC50 of 2.1 nM[1]. |
| Purity | 99.65% |