F-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112801 |
| CAS # | 2244775-31-1 |
| Pricing | inquire |
| Biological Activity | F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively[1]. |
| MWt | 519.02 |
| Formula | C₂₂H₂₇ClN₈O₃S |