Povidone K30
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-136℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives.Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
| Supplier | CD Formulation |
|---|---|
| Product # | PE-0465 |
| Pricing | , Inquire for price |
| product1 | Binder Excipients |
| Molecular Formula | (C6H9NO)n |
| Molecular Weight | 50000.0 |
| Applications | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-134℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |
| Safety | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-132℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |
| Incompatibilities | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-133℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |
| Synonyms | Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]; polyvinylpyrrolidone; povidonum; Povipharm; PVP; 1-vinyl-2-pyrrolidinone polymer |
| CAS Number | 9003-39-8 |
| Category | Binder; Solubilizer; Suspending Agents; Stabilizer; Viscosifier; Coating material |
| UNII | U725QWY32X |
| Chemical Name | 1-Ethenyl-2-pyrrolidinone homopolymer |
| Grade | Pharmceutical Excipients |
| Administration route | Oral, sublingual, ocular |
| Dosage Form | IM and IV injections; ophthalmic preparations; oral capsules, drops, granules, suspensions, and tablets; sublingual tablets; topical and vaginal preparations |
| Stability and Storage Conditions | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-131℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |
| Commonly used amount and the maximum amount | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-135℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |
| Source and Preparation | Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-136℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. |