L-006235

Supplier MedChemExpress
Product # HY-103352-25 mg
CAS # 294623-49-7
Pricing 25 mg, USD $400.0
Synonyms L-235
MWt 466.6
Formula C₂₄H₃₀N₆O₂S
Biological Activity L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss[1][2].
Purity 98.03%
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