Brefeldin A (Decumbin, Ascotoxin, Cyanein, Nectrolide, Synergisidin, BFA, CAS 20350-15-6), >99%
LC Laboratories' Product Number B-8500 - Brefeldin A (Decumbin, Ascotoxin, Cyanein, Nectrolide, Synergisidin, BFA), >99% - for research use only. Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum to the Golgi apparatus. Brefeldin A has been shown to induce apoptosis in human tumor cells via a process requiring caspase activation. Brefeldin A has been identified as an activator of the sphingomyelin signal transduction cycle.
| Supplier | LC Laboratories |
|---|---|
| Product # | B-8500 |
| Sku # | B-8500_25mg |
| Pricing | 25 mg, $78.00 |
Citations for this product:
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bioRxiv - Biochemistry 2020Quote: ... 2 μM PERK inhibitor (PERKi; gift from GSK, GSK2606414) and 10 μg/ml brefeldin A (BFA; LC Laboratories, B-8500). All compounds were diluted freshly in pre-warmed medium and applied to the cells by medium exchange.