Sivelestat sodium tetrahydrate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17443B-100 mg |
| CAS # | 201677-61-4 |
| Pricing | 100 mg, USD $420.0 |
| Synonyms | EI546 sodium tetrahydrate; LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate |
| MWt | 528.51 |
| Formula | C₂₀H₂₉N₂NaO₁₁S |
| Biological Activity | Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[1][2][3][4]. |
| Purity | 99.91% |