BI-3663
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-111546-1 mg |
| CAS # | 2341740-84-7 |
| Pricing | 1 mg, USD $550.0 |
| Biological Activity | BI-3663 is a highly selective PTK2/FAK PROTAC (DC50=30 nM), with cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-4464 (HY-124625) linked to Pomalidomide (HY-10984) with a linker[1]. Anti-cancer activity[1]. |
| Purity | 98.14% |
| MWt | 917.84 |
| Formula | C₄₄H₄₂F₃N₇O₁₂ |