Polyethylene Glycol 400
Polyethylene glycol as being an addition polymer of ethylene oxide and water. Polyethylene glycol grades 200–600 are liquids; grades 1000 and above are solids at
ambient temperatures.
Liquid grades (PEG 200–600) occur as clear, colorless or slightly yellow-colored, viscous liquids. They have a slight but characteristic odor and a bitter, slightly burning taste. PEG 600 can occur as a solid at ambient temperatures.
Solid grades (PEG>1000) are white or off-white in color, and range in consistency from pastes to waxy flakes. They have a faint, sweet odor. Grades of PEG 6003 and above are available as free_x0002_flowing milled powders
ambient temperatures.
Liquid grades (PEG 200–600) occur as clear, colorless or slightly yellow-colored, viscous liquids. They have a slight but characteristic odor and a bitter, slightly burning taste. PEG 600 can occur as a solid at ambient temperatures.
Solid grades (PEG>1000) are white or off-white in color, and range in consistency from pastes to waxy flakes. They have a faint, sweet odor. Grades of PEG 6003 and above are available as free_x0002_flowing milled powders
Supplier | CD Formulation |
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Product # | PE-0671 |
Pricing | , Inquire for price |
product1 | Humectants Excipients |
Molecular Formula | HOCH2(CH2OCH2)nCH2OH, n=7~9 |
Applications | Polyethylene glycols (PEGs) are widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations. Polyethylene glycol has been used experimentally in biodegradable polymeric matrices used in controlled-release systems. |
Safety |
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Incompatibilities |
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Synonyms | Macrogol 400 |
CAS Number | 25322-68-3 |
Category | Stabilizer; surface active agent; plasticizer; slip agent; base agent; adhesive; gloss agent; coating agent; wetting agent; emulsifier; adhesive agent; adhesion enhancer; excipient; ; Collapsing agent; Solvent; Dissolving aid |
UNII | B697894SGQ |
Chemical Name | Polyethylene Glycol 400 |
Grade | Pharmaceutical grade |
Administration route | Intramuscular injection; Intravenous injection; Nasal spray; Ophthalmic; Topical application; Oral |
Dosage Form | Injections, sprays, drops, syrups |
Stability and Storage Conditions | Store in airtight container. |
Commonly used amount and the maximum amount | The maximum dosage of each route of administration: Oral: 2.31g; General external use: 700mg/g; Rectum, cavity, urethra: 3.07g; Dental external use and oral cavity: 200mg/g; Intravenous injection: 3,2g; Local anesthesia injection; 7.881mg; Sublingual administration: 720mg/g; Other external use: 50mg; Intramuscular injection: 3.2g; Subcutaneous injection: 3.2g; Otolaryngological preparations: 50mg/mL. |
Source and Preparation | Polyethylene glycol polymers are formed by the reaction of ethylene oxide and water under pressure in the presence of a catalyst. |