Suberoyl bis-hydroxamic acid
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-W009776-50 mg |
| CAS # | 38937-66-5 |
| Pricing | 50 mg, USD $55.0 |
| Synonyms | Suberohydroxamic acid; SBHA |
| MWt | 204.22 |
| Formula | C₈H₁₆N₂O₄ |
| Biological Activity | Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 μM and 0.30 μM, respectively[1].Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways[2].Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC)[3]. |
| Purity | ≥98.0% |