Monomethyl auristatin E
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15162-10 mg |
| CAS # | 474645-27-7 |
| Pricing | 10 mg, USD $180.0 |
| Synonyms | MMAE; SGD-1010 |
| MWt | 717.98 |
| Formula | C₃₉H₆₇N₅O₇ |
| Biological Activity | Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. |
| Purity | 99.92% |