Bumetanide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-17468-500 mg |
| CAS # | 28395-03-1 |
| Pricing | 500 mg, USD $65.0 |
| Synonyms | Ro 10-6338; PF 1593 |
| MWt | 364.42 |
| Formula | C₁₇H₂₀N₂O₅S |
| Biological Activity | Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1][2]. |
| Purity | 99.91% |