1-Deoxynojirimycin hydrochloride
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin can prevent the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells through inhibiting both α-glucosidase I and II. The IC50 values are ~2 µM. Phase II clinical development of duvoglustat for Glycogen storage disease type II is ongoing.
| Supplier | BOC Sciences |
|---|---|
| Product # | 73285-50-4 |
| Pricing | Inquire |
| Cas | 73285-50-4 |
| Molecular Weight | 199.63 |
| Molecular Formula | C6H13NO4.HCl |
| Canonical SMILES | C1C(C(C(C(N1)CO)O)O)O.Cl |