Pinometostat (EPZ5676)

Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1L with Ki of 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.
Supplier Selleck Chemicals
Product # S7062
Sku # S7062-10mM/1mL
Pricing 10mM/1mL, $287.00

Citations for this product:

Feedback