Valproic acid sodium salt
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10585A-25 g |
| CAS # | 1069-66-5 |
| Pricing | 25 g, USD $80.0 |
| Synonyms | Sodium Valproate |
| MWt | 166.19 |
| Formula | C₈H₁₅NaO₂ |
| Biological Activity | Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. |
| Purity | ≥98.0% |