AG-490 (Tyrphostin B42)

Ask supplier a question | View on supplier's website

AG-490 (Tyrphostin B42, Zinc02557947) is an inhibitor of EGFR with IC50 of 0.1 μM in cell-free assays, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.

Supplier	Selleck Chemicals
Product #	S1143
Sku #	S1143-50mg
Pricing	50mg, $177.00

Citations for this product:

Long-term high-yield skeletal muscle stem cell expansion through staged perturbation of cytokine signaling in a soft hydrogel culture platform

Alexander M. Loiben, et al., bioRxiv - Bioengineering 2020

Quote: ... 1 μM AG-490 (JAK2 inhibitor with effects on EGFR kinase; Selleck Chemicals # S1143), or 10 μM BMS-345541 (IKK-1/2 inhibitor ...

Feedback