hSMG-1 inhibitor 11j

Supplier MedChemExpress
Product # HY-124719-10 mg
CAS # 1402452-15-6
Pricing 10 mg, USD $850.0
Biological Activity hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer[1].
Purity 98.91%
MWt 566.07
Formula C₂₇H₂₈ClN₇O₃S
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