HLA Class II Histocompatibility Antigen, DP Beta 1 Chain (HLA-DPB1) Antibody

HLA-DPB1 Antibody is a Rabbit Polyclonal antibody against HLA-DPB1. HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

• Supplier: Abbexa Ltd.
• Product #: abx001225-200UL
• Clonality: Polyclonal
• Conjugation: Unconjugated
• Host: Rabbit
• Tested Applications: WB, IHC
• UniProt Primary AC: P04440
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.