Pipofezine HCl
Pipofezine, also known as Azafen or Azaphen, is a tricyclic antidepressant (TCA) approved in Russia for the treatment of depression. It was introduced in the late 1960s and is still used today. Pipofezine has been shown to act as a potent inhibitor of the reuptake of serotonin. In addition to its antidepressant action, pipofezine has sedative effects as well, suggesting antihistamine activity. Other properties such as anticholinergic or antiadrenergic actions are less clear but are likely.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1128 |
| CAS # | 24853-80-3 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Azaphen HCl; Azafen; Pipofezine; Pipofezine HCl |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C16H20ClN5O |
| Molecular Weight | 333.82 |
| Elemental Analysis | C, 57.57; H, 6.04; Cl, 10.62; N, 20.98; O, 4.79 |
| IUPAC/Chemical Name | 5-methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine hydrochloride. |
| InChi Key | JVONTAXIALFQJM-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C16H19N5O.ClH/c1-19-7-9-21(10-8-19)15-11-13-16(18-17-15)22-14-6-4-3-5-12(14)20(13)2;/h3-6,11H,7-10H2,1-2H3;1H |
| SMILES Code | CN1CCN(C2=NN=C3OC4=CC=CC=C4N(C)C3=C2)CC1.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |