Binedaline
Binedaline, also known as Scha-1059, Ixprim, binodaline, is a drug that was being investigated as an antidepressant in the 1980s but never marketed. It acts as a selective norepinephrine reuptake inhibitor (Ki = 25 nM), with relatively insignificant influence on the serotonin (Ki = 847 nM) and dopamine (Ki >= 2 µM) transporters. It has negligible affinity for the α-adrenergic, mACh, H1, or 5-HT2 receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD696 |
| CAS # | 60662-16-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | SCHA-1059; SCHA 1059; SCHA1059; Sgd-Sch-1059; Binedaline; binodaline. Ixprim. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H23N3 |
| Exact Mass | 293.1892 |
| Molecular Weight | 293.414 |
| Elemental Analysis | C, 77.78; H, 7.90; N, 14.32 |
| IUPAC/Chemical Name | 1-((2-(Dimethylamino)ethyl)methylamino)-3-phenylindole |
| InChi Key | SXYFFMXPDDGOEK-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H23N3/c1-20(2)13-14-21(3)22-15-18(16-9-5-4-6-10-16)17-11-7-8-12-19(17)22/h4-12,15H,13-14H2,1-3H3 |
| SMILES Code | CN(N1C=C(C2=CC=CC=C2)C3=C1C=CC=C3)CCN(C)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |