GW806742X hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112292A-10 mM * 1 mL |
| Pricing | 10 mM * 1 mL, USD $81.0 |
| Biological Activity | GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 μM. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis[1][2]. |
| Purity | 98.77% |
| MWt | 610.01 |
| Formula | C₂₅H₂₃ClF₃N₇O₄S |