MSA-2

Supplier MedChemExpress
Product # HY-136927-50 mg
CAS # 129425-81-6
Pricing 50 mg, USD $1700.0
Biological Activity MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. MSA-2 shows EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models[1][2].
Purity 98.79%
MWt 294.32
Formula C₁₄H₁₄O₅S
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