Beta-1,3-N-Acetylglucosaminyltransferase Lunatic Fringe (LFNG) Antibody
LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1, 3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx034406-400UL |
| Pricing | 400 µl USD $601.75 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | ELISA, WB, IHC, FCM |
| UniProt Primary AC | Q8NES3 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |