Human Anti-HIV-1 Env Recombinant Antibody (clone 35O22)
Recombinant Human Antibody (35O22) is capable of binding to HIV-1 env, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 env mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 env mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody neutralized 62% of 181 pseudoviruses with a half-maximum inhibitory concentration (IC50) <50 μg ml(-1).
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-141 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 Env |
| Species Reactivity | HIV-1 |
| Type | Human IgG |
| Applications | WB, ELISA, Neut, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |