Lifarizine
Lifarizine, also known as RS-87476, is a calcium and sodium channel antagonist potentially for the treatment of stroke. Lifarizine (RS-87476) showed neuroprotective efficacy in a simplified rat survival model of 2 vessel occlusion. The effects of lifarizine on intracellular Ca2+ and glutamate exocytosis may contribute to its neuroprotective action.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD967 |
| CAS # | 119514-66-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | Lifarizine; RS-87476; RS 87476; RS87476; RS 87476-000; RS-87476-000. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C29H32N4 |
| Exact Mass | 436.2627 |
| Molecular Weight | 436.603 |
| Elemental Analysis | C, 79.78; H, 7.39; N, 12.83 |
| IUPAC/Chemical Name | 1-(Diphenylmethyl)-4-((5-methyl-2-p-tolylimidazol-4-yl)methyl)piperazine |
| InChi Key | HTDFEXRUDGWNHA-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C29H32N4/c1-22-13-15-26(16-14-22)29-30-23(2)27(31-29)21-32-17-19-33(20-18-32)28(24-9-5-3-6-10-24)25-11-7-4-8-12-25/h3-16,28H,17-21H2,1-2H3,(H,30,31) |
| SMILES Code | CC1=CC=C(C2=NC(CN3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3)=C(C)N2)C=C1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |