Rho Guanine Nucleotide Exchange Factor 1 (ARHGEF1) Antibody
Rho Guanine Nucleotide Exchange Factor 1 (ARHGEF1) Antibody is a Rabbit Polyclonal antibody for the detection of ARHGEF1.
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Supplier | Abbexa Ltd. |
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Product # | abx217576-100UG |
Pricing | 100 µg USD $406.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, IHC |
UniProt Primary AC | Q92888 |
Dry Ice | No |
Availability | Shipped within 5-12 working days. |
Note | This product is for research use only. |