| Supplier |
Creative Peptides |
| Product # |
10-101-65 |
| CAS # |
1081110-72-6 |
| Pricing |
Inquire
|
| Synonyms |
C16102; Obestatin
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| MolecularFormula |
C116H176N32O33
|
| MolecularWeight |
2546.87
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| Source |
Synthetic
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| Sequence |
- One Letter Code: FNAPFDVGIKLSGVQYQQHSQAL
- Three Letter Code: Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Gln-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2
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| ShippingCondition |
Shipped at 4°C.
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| Explanation |
Obestatin is a hormone that is produced in specialized epithelial cells of the stomach and small intestine of several mammals including humans. Obestatin was originally identified as an anorectic peptide, but its effect on food intake remains controversial.
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| Application |
Obestatin opposes the actions of ghrelin which are growth hormone secretion and increased appetite. Obestatin has opposite action to ghrelin on food intake and plays a role in energy balance. Circuit-resistance exercise resulted in a significant change in GH levels, but had no effect on plasma Obestatin levels.
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| InChIKey |
IXQOGPZNKNSCJR-QQDMDDJXSA-N
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| BiologicalActivity |
Obestatin (human) is an endogenous peptide derived from the same prepropeptide as ghrelin. Reported to suppress food intake and reduce body weight-gain in rats.
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