MK-886
Supplier | MedChemExpress |
---|---|
Product # | HY-14166-10 mg |
CAS # | 118414-82-7 |
Pricing | 10 mg, USD $144.0 |
Synonyms | L 663536 |
MWt | 472.08 |
Formula | C₂₇H₃₄ClNO₂S |
Biological Activity | MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis[1][2][3]. |
Purity | 99.77% |