Recombinant Rhesus Monkey VTCN1 Protein, hIgG1-tagged

B7H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. B7H4 is highly expressed on a number of tumor cells, including breast cancer.

• Supplier: Creative Biomart
• Product #: VTCN1-1517R