Ebselen
Supplier | MedChemExpress |
---|---|
Product # | HY-13750-10 mM * 1 mL |
CAS # | 60940-34-3 |
Pricing | 10 mM * 1 mL, USD $66.0 |
Synonyms | SPI-1005; PZ-51; CCG-39161 |
MWt | 274.18 |
Formula | C₁₃H₉NOSe |
Biological Activity | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker[1][2]. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM)[3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity[4][5]. |
Purity | ≥98.0% |